Bovine herpesvirus type 5 (BHV-5) in a calf with rabies
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چکیده
منابع مشابه
Bovine herpesvirus 5 (BHV-5) Us9 is essential for BHV-5 neuropathogenesis.
Bovine herpesvirus 5 (BHV-5) is a neurovirulent alphaherpesvirus that causes fatal encephalitis in calves. In a rabbit model, the virus invades the central nervous system (CNS) anterogradely from the olfactory mucosa following intranasal infection. In addition to glycoproteins E and I (gE and gI, respectively), Us9 and its homologue in alphaherpesviruses are necessary for the viral anterograde ...
متن کاملNeurovirulence of glycoprotein C(gC)-deleted bovine herpesvirus type-5 (BHV-5) and BHV-5 expressing BHV-1 gC in a rabbit seizure model.
Herpesvirus glycoprotein C (gC) is one of the major virus attachment proteins. Bovine herpesvirus type 1 (BHV-1) causes respiratory and genital diseases in cattle, whereas BHV-5 causes acute meningoencephalitis in calves. The gC gene sequence of these two viruses are substantially different. To determine the contribution of the BHV-5 glycoprotein gC (gC5) to the neuropathogenesis of BHV-5, we h...
متن کاملSpread of bovine herpesvirus type 5 (BHV-5) in the rabbit brain after intranasal inoculation.
Following intranasal inoculation of wild-type BHV-5 in rabbits, we studied the sequential transneuronal passage of the virus in the CNS by immunocytochemistry, histopathology, and virus isolation. At 4 and 6 days postinfection (d.p.i.), rabbits had no or mild neurological signs, and virus was isolated only from the olfactory bulbs. At 8 and 9 d.p.i., infected rabbits had severe neurological sig...
متن کاملPathogenesis of Meningoencephalitis in Rabbits by Bovine Herpesvirus Type-5 (bhv-5)
Departamento de Medicina Veterinária Preventiva-DMVP, Microbiologia e Parasitologia/DMP, Departamento de Patologia da Universidade Federal de Santa Maria-UFSM. Santa Maria, RS, Brasil. Centro de Pesquisas Veterinárias Desidério Finamor (CPVDF), Eldorado do Sul, RS, Brasil and Departamento de Microbiologia. Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil. Universidade do Esta...
متن کاملGenome of bovine herpesvirus 5.
Here we present the complete genomic sequence of bovine herpesvirus 5 (BHV-5), an alphaherpesvirus responsible for fatal meningoencephalitis in cattle. The 138390-bp genome encodes 70 putative proteins and resembles the alpha2 subgroup of herpesviruses in genomic organization and gene content. BHV-5 is very similar to BHV-1, the etiological agent of infectious bovine rhinotracheitis, as reflect...
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ژورنال
عنوان ژورنال: Pesquisa Veterinária Brasileira
سال: 2003
ISSN: 0100-736X
DOI: 10.1590/s0100-736x2003000100001